Upgrades Neutral Buy X

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Goldman

$56 $67

Initiated Outperform X

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RBC Capital Mkts

$77

Initiated Overweight X

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Wells Fargo

$72

Resumed Outperform X

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Credit Suisse

$96

Upgrades In-line Outperform X

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Evercore ISI

$60 $80

Initiated Overweight X

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Cantor Fitzgerald

$114

Resumed Buy X

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Canaccord Genuity

$90

Resumed Buy X

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H.C. Wainwright

$82

Upgrades Neutral Outperform X

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Robert W. Baird

$50

Upgrades Neutral Buy X

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Guggenheim

$50

Downgrades Outperform In-line X

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Evercore ISI

$95 $60

Upgrades Neutral Outperform X

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Credit Suisse

$99 $105

Upgrades Neutral Overweight X

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JP Morgan

$132

Initiated Neutral X

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Guggenheim

Upgrades Neutral Buy X

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BofA Securities

$162

Resumed Neutral X

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Robert W. Baird

$109

Upgrades Neutral Buy X

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Citigroup

$160 $151

Upgrades In-line Outperform X

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Evercore ISI

$144

Resumed Neutral X

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Credit Suisse

$99

Resumed Buy X

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Stifel

$179

Downgrades Overweight Neutral X

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JP Morgan

$165

Resumed Outperform X

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Wedbush

$75

Upgrades Eq-Weight Overweight X

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Morgan Stanley

$68 $83

Resumed Outperform X

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Raymond James

$80

Downgrades Outperform Mkt Perform X

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Raymond James

Upgrades Sell Neutral X

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Citigroup

Initiated Equal-Weight X

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Morgan Stanley

$92

Downgrades Outperform Neutral X

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Credit Suisse

Upgrades Eq Weight Overweight X

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Barclays

$62 $74

Initiated Neutral X

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Goldman

$63

Upgrades Hold Buy X

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SunTrust

Resumed Overweight X

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Piper Jaffray

$67

Reiterated Buy X

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Stifel

$85 $74

RARE  Ultragenyx Pharmaceutical Inc.

Ultragenyx Pharmaceutical Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the identification, acquisition, development, and commercialization of products for the treatment of genetic diseases. Its clinical-stage pipeline consists of two product categories: biologics (including a monoclonal antibody and an enzyme replacement therapy), and small-molecule substrate replacement therapies. Its product candidates under biologics category include KRN23 (UX023) and recombinant human beta-glucuronidase (rhGUS) (UX003). Its product candidates under small-molecule category include UX007 and aceneuramic acid extended-release (Ace-ER) (UX001). It is also developing recombinant human protective protein cathepsin-A (rhPPCA). KRN23 is a fully human monoclonal antibody. rhGUS is an intravenous (IV) enzyme replacement therapy. UX007 is a substrate replacement therapy. It is developing Ace-ER for the treatment of GNE myopathy. rhPPCA is in preclinical development.